Preliminary Ethanopharmacological Survey Of Medicinal Plants From Raigad District

Ethnopharmacology is the interdisciplinary science of medicinal plants utilized by humans. These people-plants (typically) relationships have historically and imminently have produced important medicines integral to modern medicine this research is to document the herbs used by traditional healers from Raigad district for treatment of various aliment. There is need to document this data as numbers of traditional healers are declining. Further it is required to establish the correlation between the reported pharmacological activities of the herbs with its actual traditional use. Through this survey various medicinal plants being used by traditional healers will be documented. Further Through systematic review of this data a plant which has been mentioned to possess Neuroprotective activity will be taken up for preclinical evaluation.. From the systematic evaluation of data obtained through Ethanopharmacological survey it was observed that herbalist are using Ruta graveolens for the treatment of Parkinson's. In Methodology,Acute toxicity study was performed on Zebrafish and parameters were observed. Rotenone induced Parkinson's disease for 3days & MSG induced neurotoxicity in zebratish for 3 days From the systematic evaluation of data obtained through Ethanopharmacological survey it was observed that herbalist claimed the use Ruta graveolense in Parkinson disease. Plant Rata graveolense have a variety of beneficial effects on nervous disorders and can be a potential candidate to be used for the treatment of PD. it can be concluded that Ruta graveolense possess good neuroprotective activity against neurotoxic model of Parkinson's disease via NMDA antagonistic and antioxidant property.