Role of Cox2 Inhibitors Used in The Treatment of Breast Cancer: An Overview

Breast cancer is a disease that is both common and complex, requiring novel therapeutic methods due to its varied genetic subtypes. The changing role of cyclooxygenase-2 (COX-2) inhibitors in the management of breast cancer is explored in this study. This article examines the molecular foundation of COX-2 participation in breast cancer and clarifies the processes by which COX-2 inhibitors exercise their anti-cancer effects. COX-2 has been linked to inflammation and the growth of cancer. The study critically assesses the present status of clinical research, covering both encouraging results and difficulties related to the use of COX-2 inhibitors in the treatment of breast cancer. The future direction of this research is highlighted, highlighting the need for refined treatment regimens and well-controlled clinical trials to establish the true efficacy and safety profile of COX-2 inhibitors in breast cancer therapy, as we navigate the complexities of patient selection, optimal dosages, and potential side effects. In the end, this review seeks to offer a thorough summary of the current situation and potential future applications of COX-2 inhibitors in the management of breast cancer.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-22
DOI
https://doi.org/10.5281/zenodo.14909824
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
0.00
Controls
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article

Role of Cox2 Inhibitors Used in The Treatment of Breast Cancer: An Overview

Zenodo (CERN European Organization for Nuclear Research)
Inflammatory mediators and NSAID effects
article

Role of Cox2 Inhibitors Used in The Treatment of Breast Cancer: An Overview

article en

Abstract

Breast cancer is a disease that is both common and complex, requiring novel therapeutic methods due to its varied genetic subtypes. The changing role of cyclooxygenase-2 (COX-2) inhibitors in the management of breast cancer is explored in this study. This article examines the molecular foundation of COX-2 participation in breast cancer and clarifies the processes by which COX-2 inhibitors exercise their anti-cancer effects. COX-2 has been linked to inflammation and the growth of cancer. The study critically assesses the present status of clinical research, covering both encouraging results and difficulties related to the use of COX-2 inhibitors in the treatment of breast cancer. The future direction of this research is highlighted, highlighting the need for refined treatment regimens and well-controlled clinical trials to establish the true efficacy and safety profile of COX-2 inhibitors in breast cancer therapy, as we navigate the complexities of patient selection, optimal dosages, and potential side effects. In the end, this review seeks to offer a thorough summary of the current situation and potential future applications of COX-2 inhibitors in the management of breast cancer.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 44%
Inflammatory mediators and NSAID effects
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