Formulation And Evaluation of Polyherbal Gel Containing Extract of Ficus Racemosa to Treat Mouth Ulcer

This study set out to create and assess an oral gel made of herbs that contained aloe Vera and powdered Ficus racemosa leaf extracts for the treatment of mouth ulcers. Indigenous populations around the world view health and culture in large part via the study of traditional medicine. In addition to having strong antimicrobial and antifungal properties, Ficus racemosa leaves are frequently used to cure a number of ailments, such as respiratory and urinary problems, wound liver disease, diabetes mellitus, diarrhea, and inflammatory conditions. While aloe Vera contains phytoconstitutes such minerals, lignin, sugars, vitamins, enzymes, saponins, salicylic acids, and amino acids, Ficus racemosa has certain critical phytoconstitutes including tannins, triterpenoids (Lanosterol), sterols, alkaloids, and flavonoids. And applied to wounds on the skin. Ficus Racemosa has key phytoconstituents, including tannins, triterpenoids (lanosterol), sterols, alkaloids, and flavonoids, whereas Aloe Vera comprises phytoconstituents such as vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids, and amino acids. It is utilized to address skin injuries and digestive issues because of its antibacterial, anti-inflammatory, and wound-healing characteristics. The herbal oral gel formulation was created using the following ingredients: Carbopol 934, propylene glycol, methyl paraben, propyl paraben, triethanolamine, aloe vera extract, Ficus racemosa extract, and the necessary quantity of distilled water. Triethanolamine was progressively added to keep the pH of the oral mucosa between 6.7 and 7.2. The physicochemical properties of the formulation were assessed, including its pH, Spreadability, viscosity, extrudability, gelling strength, and antioxidant activity. The findings showed that all physicochemical parameters were within the normal range in the optimized herbal oral formulation that contained extracts from Ficus racemosa and aloe Vera leaves. The formulation's antioxidant testing showed good results when compared to the standard. The produced herbal oral formulation proved safe, effective, and stable when used to treat mouth ulcers.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-06-27
DOI
https://doi.org/10.5281/zenodo.15755965
Primary Topic
Pharmacology and Nanomedicine Research
Type
article
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article

Formulation And Evaluation of Polyherbal Gel Containing Extract of Ficus Racemosa to Treat Mouth Ulcer

Zenodo (CERN European Organization for Nuclear Research)
Pharmacology and Nanomedicine Research
article

Formulation And Evaluation of Polyherbal Gel Containing Extract of Ficus Racemosa to Treat Mouth Ulcer

article en

Abstract

This study set out to create and assess an oral gel made of herbs that contained aloe Vera and powdered Ficus racemosa leaf extracts for the treatment of mouth ulcers. Indigenous populations around the world view health and culture in large part via the study of traditional medicine. In addition to having strong antimicrobial and antifungal properties, Ficus racemosa leaves are frequently used to cure a number of ailments, such as respiratory and urinary problems, wound liver disease, diabetes mellitus, diarrhea, and inflammatory conditions. While aloe Vera contains phytoconstitutes such minerals, lignin, sugars, vitamins, enzymes, saponins, salicylic acids, and amino acids, Ficus racemosa has certain critical phytoconstitutes including tannins, triterpenoids (Lanosterol), sterols, alkaloids, and flavonoids. And applied to wounds on the skin. Ficus Racemosa has key phytoconstituents, including tannins, triterpenoids (lanosterol), sterols, alkaloids, and flavonoids, whereas Aloe Vera comprises phytoconstituents such as vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids, and amino acids. It is utilized to address skin injuries and digestive issues because of its antibacterial, anti-inflammatory, and wound-healing characteristics. The herbal oral gel formulation was created using the following ingredients: Carbopol 934, propylene glycol, methyl paraben, propyl paraben, triethanolamine, aloe vera extract, Ficus racemosa extract, and the necessary quantity of distilled water. Triethanolamine was progressively added to keep the pH of the oral mucosa between 6.7 and 7.2. The physicochemical properties of the formulation were assessed, including its pH, Spreadability, viscosity, extrudability, gelling strength, and antioxidant activity. The findings showed that all physicochemical parameters were within the normal range in the optimized herbal oral formulation that contained extracts from Ficus racemosa and aloe Vera leaves. The formulation's antioxidant testing showed good results when compared to the standard. The produced herbal oral formulation proved safe, effective, and stable when used to treat mouth ulcers.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 46%
Pharmacology and Nanomedicine Research
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Formulation And Evaluation of Polyherbal Gel Containing Extract of Ficus Racemosa to Treat Mouth Ulcer · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS