Portable In-situ Electrospinning Devices for Personalized Healing in Emergency Wound Care

Portable in-situ electrospinning devices have emerged as a transformative solution for personalized wound care, particularly in emergency situations. These devices enable the direct deposition of nanofiber layers onto wound sites, providing a protective barrier, promoting hemostasis, and facilitating the incorporation of antimicrobial agents and healing accelerators. This review examines the technological advancements in portable electrospinning devices, various application methods, and their clinical relevance in emergency wound care. The fundamentals of electrospinning technologies, including needle-based, needle-free, melt, emulsion, and solution electrospinning, are discussed, elucidating their unique strengths and limitations. The development of battery-operated and generator-powered portable devices has expanded the scope of electrospinning applications, enabling their utilization in diverse environments such as remote locations, surgical settings, and home care. Comparative analysis of portable electrospinning devices and traditional methods for wound healing applications reveals the potential of these devices to produce nanofiber dressings with enhanced mechanical properties, barrier functions, and biocompatibility. However, challenges persist in achieving consistent fiber quality, scalability, and further refinement of device portability. The future of portable in-situ electrospinning devices presents significant potential for revolutionizing wound care, tissue engineering, and personalized medicine, with advancements in automation, material innovation, and the integration of bioactive components expected to drive further progress in this field.