Review On Efficacy of Chewable Tablets in Improving Oral Drug Delivery

Chewable tablets have gained significant attention as an effective dosage form for enhancing oral drug delivery. They offer several advantages over conventional tablets, including ease of administration, improved patient compliance, and enhanced drug bioavailability. Their rapid disintegration in the oral cavity facilitates pre-gastric absorption, potentially reducing first-pass metabolism for certain drugs. Additionally, advancements in formulation technologies, such as taste-masking, excipient selection, and controlled-release mechanisms, have further improved their efficacy and therapeutic potential. This review provides a comprehensive analysis of the role of chewable tablets in modern drug delivery systems, discussing their formulation strategies, pharmacokinetic implications, clinical applications, and challenges in development. The findings highlight the growing importance of chewable tablets in optimizing drug therapy, particularly for pediatric, geriatric, and dysphagic patients.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-10
DOI
https://doi.org/10.5281/zenodo.14997564
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
0.00
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article

Review On Efficacy of Chewable Tablets in Improving Oral Drug Delivery

Zenodo (CERN European Organization for Nuclear Research)
Drug Solubulity and Delivery Systems
article

Review On Efficacy of Chewable Tablets in Improving Oral Drug Delivery

article en

Abstract

Chewable tablets have gained significant attention as an effective dosage form for enhancing oral drug delivery. They offer several advantages over conventional tablets, including ease of administration, improved patient compliance, and enhanced drug bioavailability. Their rapid disintegration in the oral cavity facilitates pre-gastric absorption, potentially reducing first-pass metabolism for certain drugs. Additionally, advancements in formulation technologies, such as taste-masking, excipient selection, and controlled-release mechanisms, have further improved their efficacy and therapeutic potential. This review provides a comprehensive analysis of the role of chewable tablets in modern drug delivery systems, discussing their formulation strategies, pharmacokinetic implications, clinical applications, and challenges in development. The findings highlight the growing importance of chewable tablets in optimizing drug therapy, particularly for pediatric, geriatric, and dysphagic patients.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 56%
Drug Solubulity and Delivery Systems
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