A Review On Orodispersible Tablets

Pharmaceutical scientists are learning more about the physicochemical and biological factors that affect drug delivery systems' efficacy, which leads to an advancement in their sophistication. Due to improved patient compliance, orally disintegrating tablets (ODTs) have drawn a lot of attention in the last thirty years as a preferable substitute for traditional tablets and capsules. When placed on the tongue, ODTs—solid dosage forms containing medication—disintegrate quickly, often within a few seconds. The 1980s saw the introduction of ODT technologies' products to the market, which have since seen a steady increase in demand and a quick expansion of their product pipelines. New ODT technologies cover a wide range of pharmaceutical and patient demands, from improved life-cycle management to easy-to-use dosage for patients with dysphagia in the psychiatric, pediatric, and elderly populations. This has encouraged both academia and industry to generate new orally disintegrating formulations and technological approaches in this field. The aim of this article is to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects.