De Novo Histoid Leprosy - A Rare Variant of Lepromatous Leprosy

Abstract Histoid leprosy (HL) is a rare variant of lepromatous leprosy (LL) which is a highly transmissible disease. Here, we describe a de novo case of histoid leprosy. This variant typically arises in multibacillary patients who have received irregular or insufficient treatment for lepromatous leprosy. Its distinctive clinical presentation makes diagnosis challenging, potentially delaying treatment and contributing to the persistence of the disease as an endemic condition. So biopsy and histopathological examination are essential for the accurate diagnosis of histoid leprosy.