Preparation And Evaluation Of Transdermal Patch Of Lacosamide For Epilepsy

The primary aim of the work is preparation, characterization, and evaluation of lacosamide used for formulation of transdermal patch for antiepileptic activity. Then optimization of lacosamide for comtrol relese action using central composite design[CCD] In this study, we present a state-of-the-art review of the neuro physiological view of epilepsy as a disease affecting neural networks.We describe the basic and advanced principles of epilepsy as a disease affecting neural networks, based on the use of different clinical and mathematical techniques from a neurophysiological perspective, and signal the limitations of these findings in the clinical context. The patient of Epilepsy disease, they does not able to take medicine on time because of seizures may occurs in clusters ,loss of consciousness repeatedly for this purpose long acting transdermal patches are prepared. Objectives: 1. In this study, we present a state-of-the-art review of the neuro physiological view of epilepsy as a disease affecting neural networks. 2. We describe the basic and advanced principles of epilepsy as a disease affecting neural networks, based on the use of different clinical and mathematical techniques from a neurophysiological perspective, and signal the limitations of these findings in the clinical context.