An associative study determines the role of Physiological parameters with gender difference on the development of metabolic syndrome and severe metabolic syndrome

Objective & Background: High incidence of diabetes and cardiovascular risk was due to urbanization in India. In South Asia, Indians were at high risk for T2 DM, CVD, and MS. So compared certain physiological parameters in metabolic syndrome and severe metabolic syndrome of male and female. Materials and Methods: A total 211 men and 239 women participants aged ≥35 years were included in this study. The comparative study of mean and SE done by ANOVA and with the Student-Newman-Keul’s multiple comparison methods. Results: The parameters like BMI, WC, SBP, DBP found significantly high in MS, and SMS in males and females compared with controls. The PR was found high significant between groups control vs. MS and SMS groups in male, and control vs. MS in females, but insignificant in Control vs. SMS in females. Further, the physiological factors WC, SBP, DBP was high significance in group MS vs SMS in male and female, also the BMI, and PR in males, but these two variables were insignificant in females. Conclusion & Interpretation: It was observed that the physiological variables showed a significant difference with MS, and SMS in the male and female, except PR in SMS female. And all these parameters showed significance in intergroup analysis of MS and SMS in male and female groups, except BMI and PR in females.