Imaging Findings in Gorlin-Goltz Syndrome: A Case Series

Background: Gorlin-Goltz Syndrome (GGS), or Nevoid Basal Cell Carcinoma Syndrome (NBCCS), is a rare autosomal dominant disorder characterized by various clinical manifestations. This case series emphasizes the radiological features crucial for diagnosis. Methods: We present imaging findings from three cases of NBCCS, focusing on the diagnostic criteria and clinical manifestations. Results: All cases exhibited multiple odontogenic keratocysts (OKCs) of the jaw and intracranial calcifications. These radiological features are pivotal for early diagnosis. Conclusion: Radiological imaging plays a vital role in diagnosing GGS, aiding in the multidisciplinary management and improved patient outcomes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-26
DOI
https://doi.org/10.5281/zenodo.14194196
Primary Topic
Hedgehog Signaling Pathway Studies
Type
article
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article

Imaging Findings in Gorlin-Goltz Syndrome: A Case Series

Zenodo (CERN European Organization for Nuclear Research)
Hedgehog Signaling Pathway Studies
article

Imaging Findings in Gorlin-Goltz Syndrome: A Case Series

article en

Abstract

Background: Gorlin-Goltz Syndrome (GGS), or Nevoid Basal Cell Carcinoma Syndrome (NBCCS), is a rare autosomal dominant disorder characterized by various clinical manifestations. This case series emphasizes the radiological features crucial for diagnosis. Methods: We present imaging findings from three cases of NBCCS, focusing on the diagnostic criteria and clinical manifestations. Results: All cases exhibited multiple odontogenic keratocysts (OKCs) of the jaw and intracranial calcifications. These radiological features are pivotal for early diagnosis. Conclusion: Radiological imaging plays a vital role in diagnosing GGS, aiding in the multidisciplinary management and improved patient outcomes.

Zenodo (CERN European Organization for Nuclear Research)
All India Institute of Medical Sciences Raipur (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 55%
Hedgehog Signaling Pathway Studies
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