HUMAN BIOMONITORING AS ONE OF THE MAIN METHODS FOR ASSESSING THE IMPACT OF OCCUPATIONAL CHEMICAL FACTORS ON REPRODUCTIVE HEALTH

Objective. Justification of the feasibility of using human biomonitoring as one of the main methods for assessing the impact of occupational chemical factors on reproductive health. Methods. An analysis of information from the National Bureau of Statistics on medical and demographic processes in the Republic of Moldova, as well as data from the National Public Health Agency on risk factors in the workplace, was conducted. A review of scientific literature on the effects of occupational hazards on the reproductive health of workers and the assessment of the impact of occupational chemical factors on health using the human biomonitoring method was performed. The study utilized databases such as Hinari (WHO), PubMed, Medline, Medscape, NCBI, and the Cochrane Library with key terms: reproductive health, chemical pollutants, human biomonitoring. Data from the authors' own scientific research on this topic were also used. Results. In recent years, the dynamics of medical and demographic indicators in the Republic of Moldova have been characterized by negative trends. Along with many factors, reproductive health, as a component of public health, is adversely affected by occupational risk factors, including chemical pollutants. The use of biomonitoring methodology with specific biomarkers enhances the objectivity of assessing the impact of occupational chemical factors on health, including reproductive health. Human biomonitoring can be used in Moldovan healthcare practice as one of the main methods for assessing the impact of occupational chemical substances on reproductive health. Conclusions. Human biomonitoring allows for an objective assessment of the risks of disease development due to exposure to occupational chemical pollutants and provides better management of chemical risks. Biomonitoring can be used as one of the main methods for assessing the impact of occupational chemical substances on reproductive health.