Azadirachtin Indica: A Potential Substance with Anti-Cancer Properties and Activities

Neem, or Azadirachta indica, is a plant that is native to the Indian subcontinent and is a member of the Meliaceae family. Because of its many biological benefits, the Neem tree is also known as the village pharmacy. There are several applications for every part of the Neem tree, including its bark, leaves, sap, fruit, seeds, and twigs. They are commonly used to treat a variety of infections and skin conditions Azadirachtin and nimbolide are among the few bioactive components in neem that have been studied extensively, but research on a great number of additional bioactive components is warranted. The key anticancer effects of neem components on malignant cells include inhibition of cell proliferation, induction of cell death . Neem’s anticancer qualities, which have been previously investigated, include its capacity to alter the tumor environment, boost host monocyte cytotoxicity, and inhibit tumor cell growth. The goal of the current review was to examine and compile information regarding Azadirachta indica’s potential benefits for treating cancer.