Culture supernatants from cholangiocarcinoma cell lines induce the M2 phenotype of primary human monocytes.

This study aimed to elucidate the immunosuppressive characteristics of Cholangiocarcinoma or CCA by investigating the role of culture supernatants from four selected CCA cell lines, representing two major types of CCA (intra and extrahepatic CCA), on the induction of M2-polarized macrophages. The specific signaling molecules and underlying mechanisms will also be investigated.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-05
DOI
https://doi.org/10.5281/zenodo.14283711
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Culture supernatants from cholangiocarcinoma cell lines induce the M2 phenotype of primary human monocytes.

Zenodo (CERN European Organization for Nuclear Research)
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Culture supernatants from cholangiocarcinoma cell lines induce the M2 phenotype of primary human monocytes.

article en

Abstract

This study aimed to elucidate the immunosuppressive characteristics of Cholangiocarcinoma or CCA by investigating the role of culture supernatants from four selected CCA cell lines, representing two major types of CCA (intra and extrahepatic CCA), on the induction of M2-polarized macrophages. The specific signaling molecules and underlying mechanisms will also be investigated.

Zenodo (CERN European Organization for Nuclear Research)
Chulabhorn Research Institute (TH)
Openalex Percentile: Top 43%
Cholangiocarcinoma and Gallbladder Cancer Studies
DOIOpen Access PDFOpenAlex
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Culture supernatants from cholangiocarcinoma cell lines induce the M2 phenotype of primary human monocytes. · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS