Synthesis, Study the Antibacterial Activity and Liquid Crystal Phase of Some New 2,3-Dihydroquinazoline-4-one Compounds Derived From Triethyl Benzene-1,3,5-Tricarboxylate as a Basic Nucleus

ABSTRACT This study included the preparation of hydrazone derivatives (S2-S6) by reacting hydrazide compound (S1) with aromatic aldehyde substitutes and then reacting them with anthranilic acid to obtain a six-ring derived from 2,3-dihydroquinazoline-4-one (S7-S11). The validity of the prepared compounds was confirmed using physical techniques (color, melting point, radio frequency) and spectroscopic methods. (FT-IR infrared spectrum, carbon-proton NMR spectrum, 13C-NMR, and 1H-NMR). The biological activity of some of these compounds and two types of Gram-positive and Gram-negative bacteria (Staphylococcus aureus and Escherichia coli) was also studied. The properties of liquid crystals were also investigated. And the changes that occur on some compounds using hot polarized optical microscopy.