Synthesis, Characterization and In-Silico Studies of Novel Thiazolidine Analogues and Their Biological Evaluation as Potential Anti-Leishmanial Agents

In this investigation, five Schiff bases (SB-1 to SB-5) were synthesized via condensation reactions between different aldehydes and primary amines, subsequently serving as intermediates for the synthesis of four thiazolidine derivatives (TH-1 to TH-5) through cyclization with cysteine. Structural elucidation was confirmed using advanced spectroscopic techniques.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-30
DOI
https://doi.org/10.5281/zenodo.13860702
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
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article

Synthesis, Characterization and In-Silico Studies of Novel Thiazolidine Analogues and Their Biological Evaluation as Potential Anti-Leishmanial Agents

Zenodo (CERN European Organization for Nuclear Research)
Synthesis and biological activity
article

Synthesis, Characterization and In-Silico Studies of Novel Thiazolidine Analogues and Their Biological Evaluation as Potential Anti-Leishmanial Agents

article en

Abstract

In this investigation, five Schiff bases (SB-1 to SB-5) were synthesized via condensation reactions between different aldehydes and primary amines, subsequently serving as intermediates for the synthesis of four thiazolidine derivatives (TH-1 to TH-5) through cyclization with cysteine. Structural elucidation was confirmed using advanced spectroscopic techniques.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 59%
Synthesis and biological activity
DOIOpen Access PDFOpenAlex
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Synthesis, Characterization and In-Silico Studies of Novel Thiazolidine Analogues and Their Biological Evaluation as Potential Anti-Leishmanial Agents · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS