Fractal Oncology: A Theory of Membrane Polarity Collapse and Interventional Applications

This working paper introduces the Fractal Oncology model, a conceptual framework proposing that cancer may originate from a collapse in the fractal structure and functional polarity of the cell membrane. According to this hypothesis, the disintegration of spatial order within the membrane leads to biological disconnection, loss of environmental coherence, and autonomous cellular behavior characteristic of malignancy. Two experimental membrane-centered therapeutic strategies are also presented as complementary to the model: 1. **Membrane Thermal Reprogramming** – The application of thermal or cryogenic influence on the cell membrane to restore or disrupt lipid raft dynamics and membrane polarity. Zenodo Reference: https://zenodo.org/records/15213112 2. **Healthy Membrane Material Grafting** – The conceptual transfer of functional membrane components from healthy cells to malignant ones, aiming to reintroduce organizational signals and re-establish regulatory coherence. Zenodo Reference: https://zenodo.org/records/15212728 These strategies are presented purely as theoretical contributions, meant to inspire future biomedical research. The author is a licensed physician with expertise in rehabilitation medicine and an active interest in cellular-level models of disease. This document does not represent any form of clinical recommendation.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-04-14
DOI
https://doi.org/10.5281/zenodo.15215158
Primary Topic
Lipid Membrane Structure and Behavior
Type
article
Field-Weighted Citation Impact
0.00
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article

Fractal Oncology: A Theory of Membrane Polarity Collapse and Interventional Applications

Zenodo (CERN European Organization for Nuclear Research)
Lipid Membrane Structure and Behavior
article

Fractal Oncology: A Theory of Membrane Polarity Collapse and Interventional Applications

article en

Abstract

This working paper introduces the Fractal Oncology model, a conceptual framework proposing that cancer may originate from a collapse in the fractal structure and functional polarity of the cell membrane. According to this hypothesis, the disintegration of spatial order within the membrane leads to biological disconnection, loss of environmental coherence, and autonomous cellular behavior characteristic of malignancy. Two experimental membrane-centered therapeutic strategies are also presented as complementary to the model: 1. **Membrane Thermal Reprogramming** – The application of thermal or cryogenic influence on the cell membrane to restore or disrupt lipid raft dynamics and membrane polarity. Zenodo Reference: https://zenodo.org/records/15213112 2. **Healthy Membrane Material Grafting** – The conceptual transfer of functional membrane components from healthy cells to malignant ones, aiming to reintroduce organizational signals and re-establish regulatory coherence. Zenodo Reference: https://zenodo.org/records/15212728 These strategies are presented purely as theoretical contributions, meant to inspire future biomedical research. The author is a licensed physician with expertise in rehabilitation medicine and an active interest in cellular-level models of disease. This document does not represent any form of clinical recommendation.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 52%
Lipid Membrane Structure and Behavior
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