A Comparative Study to Evaluate the Efficacy of Topical use of Travoprost Vs Timolol in Open Angle Glaucoma

Introduction: This research evaluates the safety and effectiveness of the Glaucoma therapies Timolol and Travoprost in patients with Primary Open Angle Glaucoma or Ocular Hypertension. Timolol were assigned to thirty patients while Travoprost were assigned to thirty patients. Methods: A total 60 patients enrolled in this study. They were divided in two groups, 30 patients in one group. These parameters studied in present study named as gender distribution, current complaints, hypertension, the laterality, age, visual acuity, cup disc ratio, intraocular pressure and side effects. Results: A Travoprost cohort shows a higher incidence of hypertension (P=0.038), greater decrease in intraocular pressure with Travoprost versus Timolol (P<0.05), and a time dependent reduction of the cup to disc ratio with Travoprost (P<0.05). Conclusion: Difference in age distribution, gender, side effects, laterality, and blood pressure have been observed between two groups. The Travoprost reduced intraocular pressure, cup to disc ration better than this drug, and may be a better therapy for management of glaucoma.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-10-26
DOI
https://doi.org/10.5281/zenodo.14251597
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

A Comparative Study to Evaluate the Efficacy of Topical use of Travoprost Vs Timolol in Open Angle Glaucoma

Zenodo (CERN European Organization for Nuclear Research)
Glaucoma and retinal disorders
article

A Comparative Study to Evaluate the Efficacy of Topical use of Travoprost Vs Timolol in Open Angle Glaucoma

article en

Abstract

Introduction: This research evaluates the safety and effectiveness of the Glaucoma therapies Timolol and Travoprost in patients with Primary Open Angle Glaucoma or Ocular Hypertension. Timolol were assigned to thirty patients while Travoprost were assigned to thirty patients. Methods: A total 60 patients enrolled in this study. They were divided in two groups, 30 patients in one group. These parameters studied in present study named as gender distribution, current complaints, hypertension, the laterality, age, visual acuity, cup disc ratio, intraocular pressure and side effects. Results: A Travoprost cohort shows a higher incidence of hypertension (P=0.038), greater decrease in intraocular pressure with Travoprost versus Timolol (P<0.05), and a time dependent reduction of the cup to disc ratio with Travoprost (P<0.05). Conclusion: Difference in age distribution, gender, side effects, laterality, and blood pressure have been observed between two groups. The Travoprost reduced intraocular pressure, cup to disc ration better than this drug, and may be a better therapy for management of glaucoma.

Zenodo (CERN European Organization for Nuclear Research)
Baba Raghav Das Medical College (IN)
Openalex Percentile: Top 47%
Glaucoma and retinal disorders
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A Comparative Study to Evaluate the Efficacy of Topical use of Travoprost Vs Timolol in Open Angle Glaucoma · Zenodo (CERN European Organization for Nuclear Research) (2024) | TGRS Research Map | TGRS