Review On Novel Buccal Drug Delivery System and Their Current Approaches

The Buccal drug delivery system includes drug administration through the buccal mucosa, mainly composed of the lining of the cheeks. Buccal drug delivery leads direct access to the systemic circulation through the internal jugular vein bypasses drugs from the hepatic first pass metabolism leading to high bioavailability. Buccal route is an attractive route of administration for systemic drug delivery. basic components of buccal drug delivery system are bioadhesive polymers, Backing membrane, Permeation enhancers. Novel drug dosages forms such as Bio adhesive tablet, films, gel, wafers, etc. and various method used in the preparation of novel buccal drug delivary system. The objective of this article is to review buccal drug delivery by studies on current approaches.