A Review on FDA Approved Drugs for Chronic Kidney Disease

Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality occurs in general adult population, especially in people with diabetes and Hypertension. CKD is characterized by the presence of kidney damage or an estimated glomerular filtration rate of less than 60/ml/min persisting for 3months or more .Kidney function can be improved by pharmacological and Non pharmacological therapies, FDA has approved the drugs namely Empagliflozin, Nedosiran, Tenapanor, Budesonide, Vadadustat which act by improving therapeutic action. recently some advanced treatments are introduced to treat CKD by replacing or repairing of renal tissues,replace the function of natural kidney in patients with having end stage renal disease,and by modifying genes to treat CKD or by replicating the kidney structure in CKD .Non pharmacological therapies like Dietary and life style adjustments like low protein, low salt diet might help to mitigate glomerular filtrate in CKD.