Evaluation Of Anti-Inflamation & Memory Enhancing Activity For Some Pharmacological Active Extracts

It can be stated that the ethanolic extract has beneficial effects in long lasting in membrane stabilizing method, inhibition of protein denaturation method and proteinase model. It also showed a protective effect on inflammation and memory enhancing effect The mechanism may be mediated via the inhibition of prostaglandin synthesis in acute inflammatory reaction as well as inhibition of various lysosomal enzymes in chronic inflammatory responses this, justifies the claim made by Siddha and Ayurveda. The mechanism for the memory enhancing activity may be inhibition of cholinesterase enzymes in brain. Besides from the obvious therapeutic importance, these ethanolic extract of selected whole plant materials would be useful in understanding the mechanism of diseases with higher levels of cellular and molecular level. These methanolic extract could serve as lead molecules for development of prospective anti-inflammatory and memory enhancing agents. Further detailed studies are required to elucidate the exact mechanism based on molecular and genetic level responsible for activity. The present findings are significant for the development of alternative, inexpensive and perhaps safer strategies for the treatment of diseases. A detailed study is also required on isolation, characterization and in vivo study.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-09-27
DOI
https://doi.org/10.5281/zenodo.13850908
Primary Topic
Medicinal Plants and Neuroprotection
Type
article
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article

Evaluation Of Anti-Inflamation & Memory Enhancing Activity For Some Pharmacological Active Extracts

Zenodo (CERN European Organization for Nuclear Research)
Medicinal Plants and Neuroprotection
article

Evaluation Of Anti-Inflamation & Memory Enhancing Activity For Some Pharmacological Active Extracts

article en

Abstract

It can be stated that the ethanolic extract has beneficial effects in long lasting in membrane stabilizing method, inhibition of protein denaturation method and proteinase model. It also showed a protective effect on inflammation and memory enhancing effect The mechanism may be mediated via the inhibition of prostaglandin synthesis in acute inflammatory reaction as well as inhibition of various lysosomal enzymes in chronic inflammatory responses this, justifies the claim made by Siddha and Ayurveda. The mechanism for the memory enhancing activity may be inhibition of cholinesterase enzymes in brain. Besides from the obvious therapeutic importance, these ethanolic extract of selected whole plant materials would be useful in understanding the mechanism of diseases with higher levels of cellular and molecular level. These methanolic extract could serve as lead molecules for development of prospective anti-inflammatory and memory enhancing agents. Further detailed studies are required to elucidate the exact mechanism based on molecular and genetic level responsible for activity. The present findings are significant for the development of alternative, inexpensive and perhaps safer strategies for the treatment of diseases. A detailed study is also required on isolation, characterization and in vivo study.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 36%
Medicinal Plants and Neuroprotection
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