Functionalization of scaffolds with doped bioactive glass including metal traces leads to increased osteogenic potential of human mesenchymal cells

Objectives: Critical-sized bone defects pose a substantial challenge in orthopedic surgery with high mortality and increasing healthcare costs. Biomaterials for scaffold design must meet numerous criteria including adequate bioactivity, cytocompatibility, osteoinductivity, osteoconductivity, and biodegradability. [for full text, please go to the a.m. URL]