C5aR1 deficiency in osteoblasts attenuates impaired bone fracture healing in lipopolysaccharide treated mice
Objectives: In recent years evidence has accumulated that the complement system, a crucial part of innate immunity, is involved in bone turnover and the pathogenesis of inflammatory bone disorders. Our group showed that the anaphylatoxin receptor C5aR1 is upregulated during osteoblastogenesis, induces [for full text, please go to the a.m. URL]
Institutions
- Universität Ulm (DE)
- University Clinic of Traumatology (AT)
- University Hospital Ulm (DE)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2024-10-21
- DOI
- https://doi.org/10.3205/24dkou153
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00