Global circadian transcript profile of mouse Per-deficient liver tissue entrained by inverted feeding

Circadian clocks in peripheral organs are entrained by feeding. Eating in the right time is crucial to maintain metabolic health, whereas eating in the wrong time increases the susceptibility to metabolic diseases. It is unknown how change of mealtime impacts circadian transcriptomes in peripheral organs and brain. Here, we presented global circadian transcript profile of mouse Per1/2-deficient liver tissue entrained by inverted feeding to compile an atlas for mechanistic insights into how feed-fast cycle regulates circadian biology.