Effect of a session of repeated sprint training (RST) on serum adropin levels, inflammatory, and coagulation factors in healthy young men

Intense and high-speed intermittent training is recognized as an effective method for achieving rapid and extensive physiological and functional adaptations. However, it is important to consider that a single session of such exercises can exert significant physiological stress, potentially leading to adverse effects. Therefore, this study investigated the effects of a repeated sprint training (RSA) session on serum adropin, inflammatory, and blood coagulation factors. Ten healthy young men (age: 23.60 ± 2.01 years, weight: 68.60 ± 7.21 kg, body mass index: 22.00 ± 2.10 kg/m2) participated in this study. Blood samples were collected before, immediately after, and 20 minutes following the exercise protocol for measuring of adropin protein, fibrinogen, CRP, WBC, RBC, Hgb, and Hct levels. The exercise protocol consisted of 20 repetitions of different running speeds in a distance of 20 meters, with a 20-second rest period after each repetition (20*20*20). A significant increase in adropin, fibrinogen, WBCs, RBC, Hgb and, Hct levels was observed immediately after the exercise (p < 0.05). But only Adropin levels remained significantly higher than before the exercise after 20 minutes following the exercise. Therefore, even after exercise, adropin levels can remain elevated, allowing for the continuation of its positive effects. However, it is important to note that the increase in fibrinogen levels may require further investigation, particularly in relation to the use of anticoagulant agents. Therefore, when considering the implementation of these intense activities for inactive individuals, it is crucial to exercise caution and carefully assess the potential risks involved.