A randomized, placebo-controlled trial to assess the superiority of eight weeks of Grape Seed Flour supplementation for perioperative weight loss attenuation in Colorectal Cancer Cachexia and Pre-cachexia

A two-center, randomized, placebo-controlled clinical trial (RBR-5p6nv8b) that evaluated the superiority of daily supplementation with 8 grams of Grape Seed Flour, rich in polyphenols and fiber, in individuals with pre- or Cachexia associated with Colorectal cancer during the perioperative period.