Tramadol and Mental Health: A Systematic Review of Psychological Adverse Effects

This systematic review explores the psychological adverse effects associated with tramadol use, focusing on its impact on mental health. It delves into the patterns, and risk factors of psychological impairments such as anxiety, depression, cognitive dysfunction, mood disturbances, and dependence. By synthesizing current evidence, the review aims to inform clinicians, researchers, and policymakers about the psychological risks of tramadol, highlight knowledge gaps, and suggest strategies for safer prescribing practices and optimal patient outcomes.