RBARC²: Biphasic Apoptotic-Regenerative Reprogramming Based on Cannabinoids and Medusoid Coding

This project proposes a dual-phase theoretical cancer therapy. Phase 1 involves selective apoptosis of malignant cells via THC (targeting CB1/CB2 receptors). Phase 2 introduces a reprogramming strategy using gene pathways from the immortal jellyfish *Turritopsis dohrnii*, focused on FOXO, PI3K, and Wnt signaling to restore damaged cells. The RBARC² model aims to merge cannabinoid-based treatment with regenerative molecular coding. This OSF project serves as the official open-access repository for documents, figures, references, and community feedback. Principal Investigator: Ángel Díaz Morgado Organization: RBARC² Foundation Website: https://reprogramcancer.org

Publication Details

Journal
OSF Preprints (OSF Preprints)
Published
2025-01-01
DOI
https://doi.org/10.17605/osf.io/z8nua
Citations
1
Primary Topic
Zebrafish Biomedical Research Applications
Type
article
Field-Weighted Citation Impact
1.15
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article

RBARC²: Biphasic Apoptotic-Regenerative Reprogramming Based on Cannabinoids and Medusoid Coding

1 citations
OSF Preprints (OSF Preprints)
Zebrafish Biomedical Research Applications
1.15
article

RBARC²: Biphasic Apoptotic-Regenerative Reprogramming Based on Cannabinoids and Medusoid Coding

article en
1 citations

Abstract

This project proposes a dual-phase theoretical cancer therapy. Phase 1 involves selective apoptosis of malignant cells via THC (targeting CB1/CB2 receptors). Phase 2 introduces a reprogramming strategy using gene pathways from the immortal jellyfish *Turritopsis dohrnii*, focused on FOXO, PI3K, and Wnt signaling to restore damaged cells. The RBARC² model aims to merge cannabinoid-based treatment with regenerative molecular coding. This OSF project serves as the official open-access repository for documents, figures, references, and community feedback. Principal Investigator: Ángel Díaz Morgado Organization: RBARC² Foundation Website: https://reprogramcancer.org

OSF Preprints (OSF Preprints)
Openalex Percentile: Top 17%
Zebrafish Biomedical Research Applications
1.15
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RBARC²: Biphasic Apoptotic-Regenerative Reprogramming Based on Cannabinoids and Medusoid Coding · OSF Preprints (OSF Preprints) (2025) | TGRS Research Map | TGRS