CUTANEOUS SYNDROMES ASSOCIATED WITH INCREASED PERIPHERAL INSULIN RESISTANCE: A SCOPING REVIEW

This project aims to conduct a scoping review on cutaneous syndromes associated with increased peripheral insulin resistance. METHODS: The research will be an analytical and qualitative-quantitative scoping review using scientific articles from electronic platforms such as Latin American and Caribbean Health Sciences Literature (LILACS), International Health Sciences Literature (MEDLINE), Scientific Electronic Library Online (SCIELO), and the U.S. National Library of Medicine (PubMed-NCBI). To obtain the necessary data, descriptors such as Cutaneous Syndromes, Insulin Resistance, Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (T2DM), Skin, Hirsutism, Acanthosis Nigricans, Hyperkeratosis, Skin Tags (acrochordons), and Cutaneous Tumors will be used. Boolean operators “and,” “or,” and “not” will be applied, excluding incomplete, duplicate articles, those not within the established timeline, or those failing to meet inclusion criteria: publications in Portuguese, English, or Spanish, from 2005 to 2025, addressing the clinical profiles of patients with cutaneous syndromes related to increased peripheral insulin resistance. The study will be conducted by medical students at the University of Rio Verde, Aparecida de Goiânia campus, under faculty supervision and following ethical standards, as it involves no exposure of human subjects, only the analysis of previously published documents. EXPECTED RESULTS: The project will analyze the clinical profiles of patients for each cutaneous syndrome, identifying and describing manifestations associated with insulin resistance, with an emphasis on their clinical significance. Ultimately, the goal is to understand whether, according to existing literature, recognition of these cutaneous conditions can facilitate early diagnosis of insulin resistance and thereby prevent the development of T2DM and its complications.