Advances in antioxidant therapies for epidermolysis bullosa management

Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by skin and mucous membrane fragility. Oxidative stress is recognized as a major factor contributing to persistent and recurrent lesions. It can induce genomic damage, protein oxidation, lipid peroxidation, pathological angiogenesis and hypoxia. Despite the severity of the condition, therapeutic options remain limited. Here we explore the potential role of antioxidant compounds in EB patients, incorporating these compounds as a novel cornerstone in EB management.