Selectivity of compounds.

<b>(A)</b> Comparison of compound potency between (<i>left</i>) the larval stage of <i>S. mansoni</i> and <i>P. falciparum</i> 3D7 strain, and (<i>right</i>) HepG2 and <i>P. falciparum</i> 3D7. Data for <i>S. mansoni</i> and HepG2 were derived from [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012216#ppat.1012216.ref013" target="_blank">13</a>] and are shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012216#ppat.1012216.s010" target="_blank">S2 Table</a>. Correlation was performed using Spearman’s correlation test. <b>(B)</b> Selectivity index of compounds on <i>P. falciparum</i> 3D7 or Dd2 strains was calculated relative to HepG2 72 h CC₅₀ values (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012216#ppat.1012216.s010" target="_blank">S2 Table</a>). (PDF)