Structure-based SASA and ΔpKa calculations for mutated Asp, Glu, and Lys.

<p>The box and whisker plots show quartiles, median (central line), and mean (cross). (A) Distributions of predicted Asp (D), Glu (E), and Lys (K) ΔpKas (pkcalc) are shown for instEQ1 and instGE10 mutation data. Limiting thresholds of +/- 3 are applied for ΔpKa values. (B) The ΔpKa data for mutations in panel (A) are replaced with SASA, for the same subsets.</p> <p>(PDF)</p>

Publication Details

Journal
Figshare
Published
2024-11-19
DOI
https://doi.org/10.1371/journal.pone.0314022.s001
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Structure-based SASA and ΔpKa calculations for mutated Asp, Glu, and Lys.

Figshare
Genomics and Rare Diseases
article

Structure-based SASA and ΔpKa calculations for mutated Asp, Glu, and Lys.

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Abstract

<p>The box and whisker plots show quartiles, median (central line), and mean (cross). (A) Distributions of predicted Asp (D), Glu (E), and Lys (K) ΔpKas (pkcalc) are shown for instEQ1 and instGE10 mutation data. Limiting thresholds of +/- 3 are applied for ΔpKa values. (B) The ΔpKa data for mutations in panel (A) are replaced with SASA, for the same subsets.</p> <p>(PDF)</p>

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Genomics and Rare Diseases
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Structure-based SASA and ΔpKa calculations for mutated Asp, Glu, and Lys. · Figshare (2024) | TGRS Research Map | TGRS