Map quality of the P1-Fab(P1/MCA4) complex: Identification of solvent molecules.

a) Two 90° apart views of the whole cryo-EM map of the P1-Fab(P1/MCA4) complex. The map is crispy, with well-defined side chains, for most of P1 and also for the Fab variable module (VL-VH). Inset shows the map at the epitope-paratope interface (same color code as in Fig 1a). <b>b)</b> The quality of the map allowed the identification of a large number of solvent molecules in the N-terminal domain of P1. (PDF)