Description of included studies and their statistical and GRADE characteristics.

<p>Note. <b>Conclusions on effect size.</b> d/g: < 0.2 = No effect or very small; 0.2 to < 0.3 = Small; 0. to < 0.45 = Small-Medium; 0.45 to < 0.55 = Medium; 0.55 to < 0.75 = Medium-Large; 0.75 to < 1 = Large; > 1 = Very Large. R or RS: < 0.1 = No effect or very small; 0.1 to < 0.2 = Small; 0.2 to < 0.3 = Medium; 0.3 to < 0.4 = Medium-Large; 0.4 to < 0.5 = Large; > 0.5 = Very Large. OR: < 1 = No effect or very small; 1 to < 1.25 = Small; 1.25 to < 1.50 = Medium; 1.50 to < 2.50 = Medium-Large; 2.50 to < 10 = Large <b>Size of the sample.</b> < 500 = 0 point; 500 to < 1000 = 0.5 point, > 1000 = 1 point. <b>Precision of effects.</b> Large CIs > 0.25 in either direction = 0 point; Tight CIs < 0.25 in either direction = 1 point. <b>Homogeneity of effects across studies.</b> I2> 30% or Q is significant = 0 point; I2 < 30% or Q is not significant = 1 point. <b>Follow-up data.</b> Absence of follow-up data = 0 point; Presence of follow-up data (less than six months) = 0.5 point; Presence of follow-up data (six months or more) = 1 point. <b>Publication bias.</b> Not verified or not reported or verified and presence of publication bias = 0 point; Verified and absence of bias = 1 point. <b>Confounding factors.</b> No verified = 0 point; Verified = 1 point. <b>Overall Quality.</b> Total points for all elements of the GRADE system measured: < 1 = poor; 1 to < 2 = Poor to Moderate; 2 to < 3 = Moderate; 3 to < 4 = Moderate-High; 4 to 6 = High.</p> <p>(DOCX)</p>