Exit and adaptation with few or many unattached kinetochores.

<b>A)</b> Barplot presenting the percentages of the different classes of Clb2 behavior in wild-type cells arrested in nocodazole for 180 minutes. For the definition of the cell classes see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012879#pcbi.1012879.s002" target="_blank">S2A Fig</a>. <b>B)</b> Comparison between experimental and simulated values for kinetochores-attachment dynamics. Experimental data show the dynamics of cells with Mad2 Localization Index above the threshold over. Simulated data show the dynamics of unattached kinetochores (percentage of the number of unattached kinetochores per cell). <b>C)</b> Bifurcation diagrams with APC/C^Cdc20 at steady state in function of the number of unattached kinetochores superimposed with the trajectories of attachment (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012879#pcbi.1012879.g003" target="_blank">Fig 3B</a>). Representative trajectories are shown for exit (left), and adaptation with few (center) or many (right) unattached kinetochores. (PDF)