Supportive Evidence for COPD Candidate Genes.

<p>The Variant to Gene <b>(</b>V2G) score of the <i>OpenTarget</i> platform [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011079#pcbi.1011079.ref024" target="_blank">24</a>] integrates evidence for genes within +/- 500kb from the selected GWAS variant, including: (1) Molecular phenotype quantitative trait loci experiments (QTLs), (2) Chromatin interaction experiments, e.g., Promoter Capture Hi-C (PCHi-C), (3) <i>In silico</i> functional predictions, e.g., Variant Effect Predictor (VEP) from Ensembl and (4) Distance between the variant and each gene’s canonical transcription start site (TSS)</p> <p>(DOCX)</p>

Publication Details

Journal
Figshare
Published
2024-10-17
DOI
https://doi.org/10.1371/journal.pcbi.1011079.s002
Primary Topic
Diverse Scientific and Economic Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Supportive Evidence for COPD Candidate Genes.

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Diverse Scientific and Economic Studies
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Supportive Evidence for COPD Candidate Genes.

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Abstract

<p>The Variant to Gene <b>(</b>V2G) score of the <i>OpenTarget</i> platform [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011079#pcbi.1011079.ref024" target="_blank">24</a>] integrates evidence for genes within +/- 500kb from the selected GWAS variant, including: (1) Molecular phenotype quantitative trait loci experiments (QTLs), (2) Chromatin interaction experiments, e.g., Promoter Capture Hi-C (PCHi-C), (3) <i>In silico</i> functional predictions, e.g., Variant Effect Predictor (VEP) from Ensembl and (4) Distance between the variant and each gene’s canonical transcription start site (TSS)</p> <p>(DOCX)</p>

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Openalex Percentile: Top 39%
Diverse Scientific and Economic Studies
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Supportive Evidence for COPD Candidate Genes. · Figshare (2024) | TGRS Research Map | TGRS