Supportive Evidence for COPD Candidate Genes.
<p>The Variant to Gene <b>(</b>V2G) score of the <i>OpenTarget</i> platform [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011079#pcbi.1011079.ref024" target="_blank">24</a>] integrates evidence for genes within +/- 500kb from the selected GWAS variant, including: (1) Molecular phenotype quantitative trait loci experiments (QTLs), (2) Chromatin interaction experiments, e.g., Promoter Capture Hi-C (PCHi-C), (3) <i>In silico</i> functional predictions, e.g., Variant Effect Predictor (VEP) from Ensembl and (4) Distance between the variant and each gene’s canonical transcription start site (TSS)</p> <p>(DOCX)</p>
Publication Details
- Journal
- Figshare
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1371/journal.pcbi.1011079.s002
- Primary Topic
- Diverse Scientific and Economic Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00