Cell-type specific FLEXI RNAs and their host genes in MCF7 and MDA-MB-231 cancer cell lines.

<p>UpSet plots showing the distribution of (A) FLEXI RNAs, (B) FLEXI host genes, (C) FLEXI host oncogenes, and (D) FLEXI host tumor suppressor genes in MCF7 cells and MDA-MB-231 cells, compared to those in a combined dataset (Other) for HEK-293T, HeLa S4, K-562 and UHRR cellular RNA samples. FLEXI RNAs from known oncogenes [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.ref083" target="_blank">83</a>] or tumor suppressor genes [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.ref084" target="_blank">84</a>] that were detected only in MCF7 and/or MDA-MB-231 are listed below the plots. ATF3 and KLF4 were annotated as both oncogenes and tumor suppressor genes [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.ref083" target="_blank">83</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.ref084" target="_blank">84</a>].</p> <p>(PDF)</p>