Root mean square fluctuation (RMSF) plots for individual αSyn molecules in 6XYO and 6H6B, complexed with and without polyP-14 as indicated obtained from 100 ns MD simulation using Desmond.

<p>Arrows point to the α-Syn chain numbers complexed with polyP-14 that exhibit higher fluctuations in the 50–60 residue regions (highlighted in blue) compared to the fibers alone. Residues shaded in gray indicate regions of high RMSF in α-Syn fibers both with and without polyP-14. The underlying data can be found in Mendeley (see data statement for details).</p> <p>(DOCX)</p>