Effectiveness of treatment and prevalence bounce-back for the complete set of models.

<p>For each choice of the age-exposure function and endemicity setting (titles), single panels refer to a fixed combination of the assumptions of human-level regulation via anti-reinfection immunity ("Human-level", columns) and snail-level regulation via explicit snail modelling ("Snail-level", rows). The degree of regulation assumed at worm level density-dependence in egg production ("Worm-level") is highlighted with different colours, from Absent to Strong, according to the legend above each figure. A single panel shows the infection prevalence in school-aged children on the y-axis (mean of 100 stochastic realizations of the model, single runs as shaded lines) by round of treatment on the x-axis. For all models, treatment is annually administered to 5–15 years old individuals with 10 repeated rounds, a coverage of 75% of the target population, 5% of target population systematically untreated, and a drug efficacy of 86%.</p> <p>(PDF)</p>