Regio- and Stereoselective\nβ‑Sulfonylamination\nof Alkynes via Photosensitized Bifunctional N–S Bond Homolysis

Nitrogen central radicals (NCRs) are versatile synthetic\nintermediates\nfor creating functional nitrogen-containing molecules. Herein, a photosensitized\nβ-sulfonylamination of terminal alkynes as well as acetylene\nhas been established by employing <i>N</i>-sulfonyl heteroaromatics\nas bifunctional reagents (BFRs) to efficiently deliver versatile (<i>E</i>)-β-sulfonylvinylamines with excellent regio- and\nstereoselectivities. Mechanistic studies suggest a base-accelerated\nenergy transfer (EnT) photocatalysis involving aromatic NCR formation,\nradical addition to alkynes, and sulfonylation processes.