Copper-Catalyzed\nOxyfluorosulfonylation of β,γ-Unsaturated\nOximes with Sulfur Dioxide and Selectfluor for Isoxazoline-Functionalized\nAliphatic Sulfonyl Fluorides

In this report, we describe a copper-catalyzed cascade\nreaction\ninvolving oxygen radical-induced cyclization/SO<sub>2</sub> insertion/fluorination\nof β,γ-unsaturated oximes with sulfur dioxide and Selectfluor\nunder mild conditions for the synthesis of isoxazoline-functionalized\naliphatic sulfonyl fluorides. The synthetic potential of these compounds\nhas been evaluated through diverse SuFEx reactions.