Exploring theChemical Space of <i>Paenibacillus</i> NRPs and Discoveryof Paenilipoheptin B

A combination of genomic and metabolomic analyses paired with molecular networking was applied to a collection of <i>Paenibacillus</i> spp. to identify the producers of a little-studied class of lipopeptides known as paenilipoheptins. Mass spectrometry and NMR spectroscopy allowed revision of the structure of previously reported paenilipoheptin A and elucidation of the structure of novel paenilipoheptin B.