Selective Synthesisof Amines by Heterogeneous CoCatalysts via Borrowing Hydrogen Protocols

Developed Co–MgO/TiO₂ was applicable to C–N bond formation by direct amination of primary and secondary alcohols with NH₃ via a borrowing hydrogen protocol. Selective synthesis of primary, secondary, and tertiary amines was achieved by controlling the reaction conditions. Asymmetric secondary amines can be synthesized by the coupling of alcohols and amines.