StarSignDNA

Here, we introduce the StarSignDNA algorithm for mutational signature analysis, which offers efficient re-fitting and de novo mutational signature extraction. StarSignDNA is capable of deciphering well-differentiated signatures linked to known mutagenic mechanisms and suggesting clinically relevant predictions for a single patient. The package offers a command line-based interface and data visualization routines. The package is available at https://github.com/uio-bmi/StarSignDNA and can be installed via PyPI.