Homologation\nof Ketones: Direct Transformation of\nAlkyl Ketones to Aryl Ketones via Photoredox Catalyzed Deacylation-Aroylation\nSequence

Ketones, as essential functional group skeletons, have\ngarnered\nsignificant interest due to their diverse transformations. Herein,\nwe describe a versatile photoredox catalyzed deacylation-aroylation\nstrategy that enables the direct transformation of alkyl ketones to\naryl ketones. This process involves photoredox deacylation of dihydroquinazolinones\nderived from alkyl ketones to generate alkyl radicals, followed by\nsubsequent NHC-catalyzed or NHC-mediated radical aroylation.