Additional file 6 of Effects of M. tuberculosis and HIV-1 infection on in vitro blood-brain barrier function

Additional file 6: Effect of HIV-1 and/or Mtb infection(s) on ER stress. sXBP1/uXBP1 (panels A-D), BLOC1S1 (E-H), CHOP (I-L), BiP (M-P), and uXBP1 (Q-T) transcripts were assessed by SYBR-Green Quantitative RT-PCR following infection(s) with Mtb, HIV-1 Bal and/or VSV-G pseudotyped HIV-1 of astrocytes (A, E, I, M, Q), hCMEC/d3 (B, F, J, N, R), HBVP (C, G, K, O, S), and HMC3 (D, H, L, P, T). Results for 5 to 6 different donors/passages are presented in raw data normalized to the geometric mean of 18 S ribosomal gene expression in box and whiskers plots. Asterisks denote statistically significant data determined by ANOVA with Dunnett’s correction for multiple comparisons (*P < 0.05, **P < 0.01, ***P < 0.001)

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Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.29151664.v1
Primary Topic
HIV Research and Treatment
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article
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article

Additional file 6 of Effects of M. tuberculosis and HIV-1 infection on in vitro blood-brain barrier function

Figshare
HIV Research and Treatment
article

Additional file 6 of Effects of M. tuberculosis and HIV-1 infection on in vitro blood-brain barrier function

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Abstract

Additional file 6: Effect of HIV-1 and/or Mtb infection(s) on ER stress. sXBP1/uXBP1 (panels A-D), BLOC1S1 (E-H), CHOP (I-L), BiP (M-P), and uXBP1 (Q-T) transcripts were assessed by SYBR-Green Quantitative RT-PCR following infection(s) with Mtb, HIV-1 Bal and/or VSV-G pseudotyped HIV-1 of astrocytes (A, E, I, M, Q), hCMEC/d3 (B, F, J, N, R), HBVP (C, G, K, O, S), and HMC3 (D, H, L, P, T). Results for 5 to 6 different donors/passages are presented in raw data normalized to the geometric mean of 18 S ribosomal gene expression in box and whiskers plots. Asterisks denote statistically significant data determined by ANOVA with Dunnett’s correction for multiple comparisons (*P < 0.05, **P < 0.01, ***P < 0.001)

Figshare
University of Cape Town (ZA), The Francis Crick Institute (GB), Imperial College London (GB)
Good health and well-being
Openalex Percentile: Top 47%
HIV Research and Treatment
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