Additional file 14 of Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis

Supplementary Material 14 Fig. S10: Co-cultivation with FB2-CAFs influences the expression of fatty acid metabolism-related targets upon ALK signaling perturbation via brigatinib (A) and lorlatinib (B) in H2228 and H3122 cells (n = 3). Data are presented as mean ± SD. #, p≤0.05; ##, p≤0.01; ####, p≤0.0001 compared to corresponding DMSO controls. *, p≤0.05; **, p≤0.01; ***, p≤0.001; ****, p≤0.0001 compared to brigatinib- or lorlatinib-treated mono-cultures, respectively.