Additional file 1 of Pan-cancer analysis of homologous recombination deficiency and homologous recombination repair–associated gene alterations in solid tumors from a large Asian cohort

Supplementary Material 1: Supplementary Table 1. HRR genes list. Supplementary Table 2. Tumor suppressor genes list. Supplementary Figure 1. Heatmap of HRD, LST and TAI events on 22 chromosomes. Heatmap of (A) HRD, (B) LST, and (C) TAI events per 3-megabase interval on 22 autosomal chromosomes. Supplementary Figure 2. HRD correlation with clinical genomic features. HRD correlation with (A) Stage, (B) Age, (C) Sample source, (D) histological subtype in lung cancer, (E) histological subtype in cervical cancer, (F) PD-L1 status after excluding MSI-H and POLE-mutated tumors, (G) TMB, (H) TMB after excluding MSI-H and POLE-mutated tumors, (I) TMB in TCGA dataset, (J) TMB after excluding MSI-H and POLE-mutated tumors in TCGA dataset, (K) TP53 biallelic status and TMB, (L) TP53 biallelic status and TMB after excluding MSI-H and POLE-mutated tumors, (M) WGD, and (N) MATH.