Supplemental Figures S1

Supplemental Figure 1: Dapagliflozin does not alter insulin secretion in situ a. Insulin secretion in response to 12.5 µM Dapagliflozin (Dapa). 4G = 4 mM glucose, 8G = 8 mM glucose (n=3 WT mice). b. Average secretion of insulin during steady state for a. (n=3 WT mice). c. Insulin secretion in response to 100 nM Dapa and 100 nM AVP (n=4 WT mice). d. Average secretion of insulin during steady state for c. (n=4 WT mice). Differences in b. and d. are based on paired sample t-test and data are represented as boxplots with median and quartiles indicated. p<0.05=*