Additional file 1 of Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol

Supplementary Material 1: Supporting Information. The online version contains Supplementary Information, which include Supplementary Figures. Supplementary Figure S1– S9 show physicochemical characterization of N-CHOL-lipos, influence of a micropinocytosis inhibitor on cellular uptake of N-CHOL-lipos, membrane fusion of N-CHOL-lipos, comparison between N-CHOL-lipos and N-7DHC-lipos in terms of inducing oxidative stress increase and DNA damage, proposed mechanism for 7DHC-induced autooxidation under radiation, cell toxicity of N-7DHC-lipos, individual tumor growth curves, and H&E staining results. Supplementary Table S1 shows CBC results

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Publication Details

Journal
Figshare
Published
2025-01-01
DOI
https://doi.org/10.6084/m9.figshare.28666191
Primary Topic
Ferroptosis and cancer prognosis
Type
article
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Additional file 1 of Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol

Figshare
Ferroptosis and cancer prognosis
article

Additional file 1 of Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol

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Abstract

Supplementary Material 1: Supporting Information. The online version contains Supplementary Information, which include Supplementary Figures. Supplementary Figure S1– S9 show physicochemical characterization of N-CHOL-lipos, influence of a micropinocytosis inhibitor on cellular uptake of N-CHOL-lipos, membrane fusion of N-CHOL-lipos, comparison between N-CHOL-lipos and N-7DHC-lipos in terms of inducing oxidative stress increase and DNA damage, proposed mechanism for 7DHC-induced autooxidation under radiation, cell toxicity of N-7DHC-lipos, individual tumor growth curves, and H&E staining results. Supplementary Table S1 shows CBC results

Figshare
University of North Carolina at Chapel Hill (US), Emory University (US), University of Washington (US)
Good health and well-being
Openalex Percentile: Top 36%
Ferroptosis and cancer prognosis
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