Cinnamoylphenethyl amides from <i>fissistigma bracteolatum</i> and their anti-inflammatory activities
Two new (<b>1</b>–<b>2</b>) and six known (<b>3</b>–<b>8</b>) cinnamoylphenethyl amides were isolated from <i>Fissistigma bracteolatum</i>. The structural configurations of <b>1</b> and <b>2</b> were determined through comprehensive spectroscopic characterisation, with mainly by NMR data analyses. Compounds <b>1</b>–<b>8</b> were assessed for the suppression on NO production. Among these, compounds <b>4</b>–<b>5</b> revealed inhibitory effects with IC<sub>50</sub>: 1.45 ± 0.16 and 21.46 ± 1.33 μM, respectively, indicating potent and moderate activity profiles.
Publication Details
- Journal
- Figshare
- Published
- 2025-01-01
- DOI
- https://doi.org/10.6084/m9.figshare.29876050.v1
- Primary Topic
- Traditional and Medicinal Uses of Annonaceae
- Type
- article
- Field-Weighted Citation Impact
- 0.00